The Effect of Cultivated Wild Ginseng Extract on Preadipocyte Proliferation

Kim, Byoung-Woo; Kwon, Ki-Rok

Keywords: Cultivated wild ginseng; preadipocytes; adipocytes; obesity

DOI: http://dx.doi.org/10.3831/KPI.2007.10.3.029

Objectives The purpose of this study is to investigate the effects of cultivated wild ginseng extract on primary cultured preadipocyte and adipocytes. Methods Diminish preadipocyte proliferation does primary role to reduce obesity. So, preadipocytes and adipocytes were performed on cell cultures with using Sprague-Dawley rats and treated with 0.01-1mg/ml cultivated wild ginseng extract. Result At all concentrations, cultivated wild ginseng extract wasn't show the suppress proliferation of preadipocytes significantly and failed to show effects on decomposition of adipocytes except high dosage. Conclusion Based on these findings, cultivated wild ginseng is not a suitable choice for the treatment of localized obesity.