Effect of Artemisia capillaries on Gene Expression of Lipid Metabolism in Rat

Jang, Woo-Seok

Keywords: Artemisia capillaries; Hyperlipidemia; Gene expression

DOI: http://dx.doi.org/10.3831/KPI.2011.14.3.063

Objectives : The purpose of this study is to evaluate the effect of Artemisia capillaries on gene expression of lipid metabolism in rats. Methods : The author performed several experimental items to analyze the total cholesterol and triglyceride in liver tissue, the gene expressions of CYP7A1 and HMG-CoA reductase. Results : 1. In Artemisia capillaries group, the levels of total cholesterol in liver tissue were significantly decreased. 2. In Artemisia capillaries group, the ratios of CYP7A1, HMG-CoA reductase were as same as the normal group. Conclusions : From the above results, Artemisia capillaries can be used to treat hyperlipidemia.