A Clinical Study on Blood Lipids as a Risk Factor of Cerebral Infarction

Son, Yeon-Hui; Lee, Sang-Hee; Kim, Jae-Kyu; Jeong, Hyun-Yun; Kim, Young-Kyun; Kwon, Jung-Nam

Keywords: acute brain infarction; silent brain infartion; case-control study; risk factor; blood lipid

DOI: http://dx.doi.org/10.3831/KPI.2008.11.4.049

Objective The purpose of this case-control study was done to examine the relationship among the acute brain infarction, silent brain infarction and blood lipids. Methods We compared the components of blood lipids among acute brain infarction patients group (n=99), silent brain infarction patients group(n=101) and controls group (n=153). The analysis of the data was done by Frequency Analysis, one-way ANOVA, Post Hoc Test(Duncan), Pearson's Correlation. Results The results were as follows. High density lipoprotein cholesterol(HDL-Chol) was significantly lower in patients of acute brain infarctions group. The blood levels of total cholesterol(T-Chol) was significantly higher in patients of silent brain infarctions. A study on the relationship among the significant variables ; In T-Chol and HDL-Chol, DM(No=0, Yes=1) and Age, they had positive correlation each other. Between Sex(Female=0, Male=1) and HDL-Chol, Age and HDL-Chol, DM and HDL-Chol, they had negative correlation each other. Conclusions These results suggest that low HDL-Chol may be risk factor of acute brain infarction.